Experimental Epilepsy Group

Department of Clinical and Experimental Epilepsy


Institute of Neurology

 

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Positions available:

  

Two research positions: Post Doctoral Research Associate and Senior Research Technician

 

Applications are invited for two Research positions investigating mechanisms of synaptic plasticity in interneurons, within the Department of Clinical and Experimental Epilepsy based at the Institute of Neurology, Queen Square, under the supervision of Professor Dimitri Kullmann.

 

Post 1 - Post Doctoral Research Associate

The purpose of this post is to investigate the mechanisms of long-term plasticity in hippocampal and cortical interneurons. The post involves electrophysiological and optical methods to investigate long-term potentation in GABAergic interneurons.

 

It is essential that candidates hold a PhD in neuroscience, have experience of cellular electrophysiology and research experience in whole-cell patch-clamp and/or live-cell fluorescence microscopy. In addition, candidates should have knowledge of in vitro patch clamp methods, an in-depth understanding of biophysics and quantitative methods and a background in confocal or multiphoton fluorescence microscopy.

 

The post is available from 1 October 2009 and is funded by by a grant from the European Research Council for 3 years. Starting salary on UCL Grade 7, range £28,839- £35,469 pa, according to age and experience, plus £2,781 pa London Allowance, superannuable.

 

Post 2 – Senior Research Technician

 

This post involves histological methods to characterise neurons with immunohistochemical and morphological methods.

 

It is essential that candidates have experience of cellular neuroscience, research experience of neuroanatomical methods, a background in neuroscience or cell biology, knowledge of neuroanatomy, and histological expertise.

 

The post is available from 1 October 2009 and is funded by by a grant from the European Research Council for 3 years. Starting salary on UCL Grade 7, range £28,839- £35,469 pa, according to age and experience, plus £2,781 pa London Allowance, superannuable.

 

Informal inquiries regarding the posts can be directed to Professor Dimitri Kullmann (d.kullmann[at]ion.ucl.ac.uk) using ‘Research position’ in the subject.

 

Further details of the research group are available at: http://www.ion.ucl.ac.uk/~dkullman

Further details should be obtained from www.ion.ucl.ac.uk/docs/fp-090801.doc, or from : Samantha Robinson, Personnel Officer, Institute of Neurology, 23 Queen Square, London, WC1N 3BG (email: personnel@ion.ucl.ac.uk) stating which post you are applying for.

 

Closing date: 1 November 2009

 

 

Recent vacancies: Post Doctoral Research Associates – 4 posts   

                              

Experimental Epilepsy and Molecular Neurosciences Groups

Applications are invited for four post-doctoral research positions investigating novel lentiviral-based strategies to treat focal epilepsy in the Experimental Epilepsy and Molecular Neuroscience Groups, based at the Institute of Neurology, Queen Square. These posts are funded by grants from the MRC, Wellcome Trust, and Epilepsy Research UK for 2 or 3 years. All posts are available from 1 September 2009.

 

Post 1 - Post Doctoral Research Associate: Cellular Neuroscience

This senior post doctoral research position involves using Lentiviral mediated shRNA to alter the course of in vivo models of focal neocortical epilepsy. The post involves in vivo models of epilepsy, video EEGs, in vitro electrophysiology, and tissue culture.

 

Applicants should have a PhD and several years’ post-doctoral research or equivalent in a relevant subject, experience of in vivo administration of viral particles and reagents, in vivo models of epilepsy, in vitro patch clamp methods, in-depth understanding of biophysics and quantitative methods and a background in molecular biology. The post is available from 1 September 2009 and is funded by the Wellcome Trust for 3 years.

 

Starting salary on UCL Grade 8 in the range £36,532 - £38,757pa plus £2,781 London Allowance, superannuable.

 

Post 2 - Post Doctoral Research Associate: Cellular Neuroscience

This post doctoral research position focuses on the design and construction of lentiviral vectors to deliver cDNAs encoding ion channels and related proteins to epileptic foci. The post involves extensive molecular biology, and in vitro patch clamp recordings.

 

Applicants should have a PhD or equivalent in a relevant subject, experience of molecular biology; patch clamp recordings in vitro, a background in molecular biology and bioinformatics, in vitro patch clamp methods and an in-depth understanding of biophysics and quantitative methods. The post is available from 1 September 2009 and is funded by the MRC for 3 years.

 

Starting salary on UCL Grade 7 in the range £28,839- £30,594pa plus £2,781 London allowance, superannuable.

 

Post 3 - Post Doctoral Research Associate: Cellular Neuroscience

This post doctoral research position will involve characterising the biophysical impact of lentivirally-driven changes in gene expression in epileptic foci. The post involves extensive in vitro and in vivo electrophysiology.

 

Applicants should have PhD or equivalent in a relevant subject, experience of patch clamp recordings in vitro, in vitro patch clamp methods and an in-depth understanding of biophysics and quantitative methods. The post is available from 1 September 2009 and is funded by the MRC for 3 years.

 

Starting salary on UCL Grade 7 in the range £28,839 - £30,594pa plus £2,781 London allowance, superannuable.

 

Post 4 - Postdoctoral Research Associate: Cellular Neuroscience

Potassium channels in focal epilepsy. This post doctoral research position involves exploring the role of potassium channels, both endogenous and lentivirally-expressed, in the development and treatment of epilepsy. The post involves immunohistochemistry, in vitro and in vivo electrophysiology.

 

Applicants should have a PhD or equivalent in a relevant subject, experience of patch clamp recordings in vitro, in vitro patch clamp methods, an in-depth understanding of biophysics and quantitative methods and a background in immunohistochemistry. The post is available from 1 September 2009 and is funded by ERUK for 2 years.

 

Starting salary for this post on UCL Grade 7 in the range £28,839- £31,513pa plus £2,781pa London Allowance, superannuable.

 

 

Further details of the research groups are available at:  http://www.ion.ucl.ac.uk/research/epilepsy/epilepsy_intro.htm and http://www.ucl.ac.uk/~skaasns/

 

Further details of the posts can be obtained from Samantha Robinson, Personnel Officer, UCL Institute of Neurology, 23 Queen Square, London WC1N 3BG (tel: 020 7676 2191 email personnel@ion.ucl.ac.uk).

 

Alternatively, details can be obtained from the Institute’s website - http://www.ion.ucl.ac.uk/about/vacancies.htm

Informal inquiries regarding the posts can be directed to Dr. Stephanie Schorge (s.schorge[at]ion.ucl.ac.uk), Professor Dimitri Kullmann or Professor Matthew Walker using ‘Post doctoral position’ in the subject.

 

Closing date: 1 July 2009.

 

 
 

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